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Sociadade Brasileira de Imunologia
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Scientific program

FINAL PROGRAM
TIME
WEDNESDAY, November 3rd 2010
Section of Clinical Immunology
8am - 2pm
Registration
9am - 10:30am

RT 1. Clinical Immunology I
RESPIRATORY VIRUSES

• Chair: Renato Stein (PUCRS, Brazil)

- Renato Stein (PUCRS, Brazil)
Viral infections in Brazil and development of respiratory diseases
- Thais Mauad (USP, Brazil)
Lung pathology and immune response during H1N1 epidemy in Brazil
-Barbara Porto (PUCRS, Brazil)Modulation of murine bone marrow-derived dendritic cells by H1N1 virus haemagglutinins
- Nicholas Lukacs (USA)
Innate immune responses dictate respiratory virus-induced pathogeneses

RT 2. Clinical Immunology II
AUTOIMMUNITY
• Chair: Jorge Kalil (FMUSP, Brazil)

- Jorge Kalil (FMUSP, Brazil)
Recent advances in immunopathology of rheumatic fever
- Mark Hogarth (HMcPherson, Australia)
Roles of Fc Receptors and immune complexes in the heterogeneity of autoimmune arthritis
- Angelina Bilate (NY Univ., USA)
Regulatory role of plasmacytoid dendritic cells in autoimmune encephalomyelitis
- Willem van Eden (Univ. Utrecht, Holland)
Heat shock proteins for the immunotherapy of chronic inflammatory diseases.
10:30am - 11am
COFFEE BREAK
11am - 12pm
RT 3. Clinical Immunology III
STEM CELL THERAPIES

• Chair: Júlio Voltarelli, (USP, Brazil)

- Nance Nardi (UFRGS, Brazil)
Stem cells and their niches- Implications for therapy
- Lúcia Silla (UFRGS, Brazil)
Cancer immunotherapy
- Júlio Voltarelli (USP, Brazil)
Hematopoietic stem cell transplantation for autoimmune diseases
RT 4. Clinical Immunology IV
HIV - IMMUNOPATHOLOGY AND VACCINES

• Edécio Cunha-Neto (USP, Brazil)

- Douglas Nixon (UCSF, USA)
EndogenousA retroelement immunity in HIV-1 infection
- Daniela Santoro Rosa (USP, Brazil)
Advances in the development of a novel HIV vaccine
- Maria Teresa M. Giret (USP, Brazil)
GBV-C - HIV Interactions
- Benedita Rocha (Necker, France)
CD8 dysfunction in HIV infection associates to major modifications of T-bet expression
12pm - 2pm
LUNCH
2pm - 3:45pm
RT 5. Clinical Immunology V
IMMUNOGENETICS - BEYOND THE CLASSICAL HLA GENES

• Chair: José Artur Bogo Chies (UFRGS, Brazil)

- Sérgio Crovella (UFPE, Brazil)
Immunogenetics and infection
- Eduardo José Melo dos Santos,(UFPR,Brazil)
Immunogenetics and ancestrality - Maria Luiza Petzl-Erler,(UFPR,Brazil)
Immunogenetics, human populations and pemphigus foliaceus
- Eduardo Antônio Donadi (USP-RP, Brazil)
Immunogenetics and cancer
RT 6. Clinical Immunology VI
EMERGING CONCEPTS IN ALLERGY

• Chair: Momtchillo Russo (USP, Brazil)
- Momtchillo Russo (USP, Brazil)
Asthma models for a complex syndrome
- Valérie Verhasselt (France)
Post-natal maternal programming of allergic diseases
- Luciana Mirotti (USP, Brazil)
Food Allergy and Behavior
- Denise Fonseca (USP, Brazil)
Allergen-free immunotherapy of experimental asthma
4pm - 5pm
RT 7. Clinical Immunology VII
IMMUNODEFICIENCIES

• Chair: José Marcos Cunha (USP, Brazil)
- Karina Salmazi (USP, Brazil)
NKT in primary deficiencies
- João Bosco Oliveira (NIH,USA)
Human disorders of apoptosis: from the bench to the bedside and back
-Luiz Vicente Rizzo, Hospital Albert Einstein, SP
Regulation of the immune response in immunodeficiency, or how can you drive a car missing the steering wheel
- Anete Grumach (USP, Brazil)
Complement deficiences: new findings
RT 8. Clinical Immunology VIII
VIRUSES IN CLINICAL PRACTICE

• Chair: Niels Olsen (USP, Brazil)
- Nancy Bellei (UNIFESP, Brazil)
The H1N1's epidemy
- Luis Fernndo Camargo Aranha (USP, Brazil)
CMV infection in Immunocompromised hosts
- Ana Paula Lepique (USP, Brazil)
Human Papillomavirus associated tumor microenvironment and modulation of host´s immune responses
- João Trindade Marques (UFMG, Brazil)
The mechanism of dsRNA-induced apoptosis by Interferon Regulatory Factor 3
5pm - 5:30pm
COFFEE BREAK
5:30pm - 6:30pm

RT 9. Frontiers in imaging
• Chair: Camila Oliveira (UFBA, Brazil)

- Michael Dustin (New York Univ, USA)
Distinctions between effector cells and regulatory cell immunological synapses
- Gabriel Victora (NYU & The Rockefeller Univ., USA)
Multiphoton Microscopy using Photoactivatable Green Fluorescent Protein Reveals Mechanisms that Govern Germinal Center Selection
- Antonio Rothfuchs (Karolinska Inst, SW)
"Visualization of antigen recognition by CD4+ T cells during mycobacterial infection"

6:30pm - 6:45pm
Opening Ceremony
6:45pm - 7:45pm
C1 - Opening Conference. Philippa Marrack (National Jewish Health , Denver, CO) - Sex and B cells
• Chair: Patricia Bozza (FIOCRUZ, Brazil)
7:45pm - 8:45pm
POSTERS & HAPPY HOUR
8:45pm - 9:45pm WELCOME PARTY
Program subject to change *


TIME
THURSDAY, November 4th 2010
8am - 9am
Immunology Courses
9am - 10:30am
RT 10. Immunity against intracellular bacteria
• Chair: André Báfica (UFSC, Brazil)

- Carl Feng (NIH, USA)
Interferon response to Mycobacterium tuberculosis
- Sergio Costa Oliveira (UFMG, Brazil)
The role of type I interferon signaling in host susceptibility to an
intracellular bacterial infection
- Dario Zamboni (USP, Brazil)
Inflammasome activation in response to bacterial infection
RT 11.Tumor Immunology.
• Chair: José Alexandre Barbuto (USP, Brazil)

- Matthew Mescher (Minnesota Univ., USA) - CD8 T Cell Activation and Tumor Immunotherapy
- Hildegund Ertl (Wistar, USA) - Cancer Vaccines: the Sisyphean challenge.
- Ana Carolina Monteiro (INCA-RJ, Brazil) - Immune interplay between osteolytic disease and bone metastasis
- Ana Paula Souza (PUCRS, Brazil) - Priming and differentiation of CD4+ T cells against a non-tumor antigen is unaffected in melanoma bearing mice
10:30am - 11am
COFFEE BREAK
11am - 12pm
C2 - Enhancing the effectiveness of vaccines by targeting antigens to dendritic cells
Ken Shortman, WEHI, Australia
• Chair: Ana Maria Caetano Faria (UFMG, Brazil)
12pm - 2pm LUNCH
12:45pm - 1:30pm

Technical Conference Life Technologies

Introducing Attune: The World's First Acoustic-Focusing Cytometer
Suzanne Schloemann
Field Applications Specialist
Flow Cytometry Systems
Life Technologies

2pm - 3:45pm
RT 12. Viral immunity
• Chair: Marcelo Bozza (UFRJ, Brazil)

- Wilson Savino (FIOCRUZ, RJ)
Non-lymphoid cell targets in HTLV-1 infection
- Guilhermina Melendi (Argentina)
Dengue infection during pregnancy
- Johan Van Weyenbergh (CPqGM-BA, Brazil)
Type I IFN as a key player in both pathogenesis and therapy of HTLV-1 associated leukemia and neurodegenerative disease
- Luiz Rodrigues (UNIFRA, Brazil)
- Rescue of CD4 T cells with IL-21 during immunosuppression
RT 13. New insights into lipid mediators
• Chair: Lucia Faccioli (USP, Brazil) e Sonia Jancar (USP, Brazil)

- Carlos Henrique Serezani (Univ. Michigan, USA)
Leukotrienes, microRNAs and MyD88: boosting up innate immune responses
- Colin Funk (Canada) Eicosanoid Lipid Mediator Pathways in Health and Disease
- Michael Wakelam (Cambridge, UK)
Phospholipases D signalling in malignancy
- Alexandra I. Medeiros (UNESP, Brazil)
Lipid mediators in lung antimicrobial function
4pm - 5pm
C3 - What do CD4 T cells see in type-1 diabetes in the NOD Mouse?
John Kappler, National Jewish Health, Denver, USA
• Chair: Wilson Savino(FIOCRUZ, Brazil)
5pm - 5:30pm
COFFEE BREAK

5:30pm - 6:30pm
C4 - Immunity to influenza viruses
Adolfo Garcia-Sastre, Mount Sinai, USA
• Chair: Ricardo Gazinelli (UFMG, Brazil)
6:30pm - 7:30pm
POSTERS & HAPPY HOUR
7:30pm - 8:30pm
General Assembly of the Brazilian Society of Immunology
Program subject to change *


TIME
FRIDAY, November 5th 2010
8am - 9am
Immunology Courses
9am - 10:30am
RT 14. Sepsis
• Chair: Fernando Q. Cunha (USP, Brazil)

- Fernando Cunha (USP, Brazil)
Protecting effects of hidrogen sulfide and IL-33 in sepsis
- Gláucia Furtado (Mount Sinai, USA)
A novel model for sepsis.
- Fernando A. Bozza (FIOCRUZ, Brazil)
New control mechanisms of vascular permeability in sepsis and influenza
RT 15. Vaccines and viral vectors.
• Chair: Oscar Bruna-Romero (UFMG, Brazil)

-Tomas Hanke (Oxford, UK)
Tackling the HIV-1 diversity
- Flávio da Fonseca (UFMG, Brazil) Poxvirus/MVA-based vaccines in the Brazilian context: Aspects and current Status
- Myrna Bonaldo (FIOCRUZ, Brazil)
Yellow fever
- Alexandre Machado (FIOCRUZ, Brazil) Influenza viruses as vaccine vectors
10:30am - 11am
COFFEE BREAK
11am - 12pm
C5 - Mechanisms of disease and protection in experimental dengue infection
Mauro M. Teixeira, UFMG, Brazil
• Chair: Fernando Q. Cunha(USP, Brazil)
12pm - 2pm
LUNCH
12:45pm - 1:30pm

Techinical Conference PerkinElmer

Alpha: alternativa mais rápida e fácil para ELISA
Renata Romanato

Technical Conference BD

- Citometria de Fluxo
2pm - 3:45pm
RT 16. Clinical Immunology I
TRANSPLANTATION IMMUNOLOGY AND CELL THERAPY

• Chair: Ana Carla Goldberg (USP, Brazil)

- Fernanda Pinto Mariz (Univ. Pierre et Marie Curie, Paris)
VLA-4 is a disease progression biomarker and a potential target for immunotherapy in Duchenne muscular dystrophy
- Luciana Cavalheiro Marti (Hospital Albert Einstein, SP)
The importance of Interleukin-7 on Cord Blood T Cells Expansion: A Critical Step on the way to Adoptive Immunotherapy
- Adriana Bonomo (INCA-RJ, Brazil)
Nod2 -/- dendritic cells protect mice from GVHD induced death without affecting disease severity
RT 17. B-cell biology
• Chair: Alberto Nóbrega (UFRJ, Brazil)

- John Cambier (Denver, USA)
Autoimmunity, Infection and B Cell Anergy; Connections and Disconnections
- Alberto Nóbrega (UFRJ, Brazil)
Role of TLRs in B cell development
- Harry W. Schroeder (Univ. Alabama, USA)
Development of the antibody repertoire: the illusion of free will
- Andre Vale (Univ. Alabama, USA)
"New evidence in favor of self-antigen as a critical driving force in the development of the natural antibody repertoire."
4pm - 5pm
C6 - Role of CMV infection during immunosenescence
Graham Pawelec, Univ. Tubingen, Germany
• Chair: Moisés Bauer (PUCRS, Brazil)
5pm - 5:30pm
COFFEE BREAK
5:30pm - 6:30pm
C7 - The human antibody response to HIV
Michel Nussenzweig, The Rockefeller University, USA
• Chair: Júlio Scharfstein(UFRJ, Brazil)
6:30pm - 7:30pm
POSTERS & HAPPY HOUR
7:30pm - 10:30pm
Dinner Party for invited speakers
Program subject to change *


TIME
SATURDAY, November 6th 2010
8am - 9am
Immunology Courses
9am - 10:30am
RT 18. T-cell Biology
• Chair: João Viola (INCA, Brazil)

Stephen M. Hedrick (UCSD, USA) - TGF-beta control of regulatory T cell development and function
- Mark Kaplan (Indiana Univ., USA) - Transcriptional regulation of T helper subset differentiation
- Thiago Detanico (National Jewish, USA) - Peripheral and central CD4 T cell Tolerance to IgV derived-peptides
- Miriam B.F. Werneck (INCA, RJ) - Loss of the tumor suppressor Snf5 reveals an essential role for the T cell receptor in lymphomagenesis and tumor progression
10:30am - 11am
COFFEE BREAK
11am - 11:30am
C8 - Viruses, inflammation and cancer.
Sérgio Lira (Mount Sinai, USA)
Chair: Manoel Barral-Netto
11:30am - 12:15pm
C9 - Closing Conference
Heme and inflammatory imbalance: role on the pathogenesis of malaria and visceral leishmaniasis.
Aldina Barral, FIOCRUZ, Salvador (BA) • Chair: João Santana da Silva(USP, Brazil)
12:30pm - 2pm
AWARDS
Program subject to change *

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